NMRK1

Across TCGA cell cohorts, NMRK1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NMRK1-associated genes across cancer lineages are WFDC6, VSIG4, and CLVS1. Each is linked with NMRK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMRK1-to-partner and partner-to-NMRK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, WFDC6 grouped by NMRK1-low versus NMRK1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRK1→partner) and Y-score (partner→NMRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	WFDC6 →	+0.050	+4.887	<.001	.009	3	1
LARGE_INTESTINE	VSIG4 →	+0.031	+2.791	<.001	.005	3	1
LARGE_INTESTINE	CLVS1 →	+0.092	+3.285	.004	.007	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

WFDC6 by NMRK1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →