NMRAL2P

Across TCGA patient cohorts, NMRAL2P mutation is significantly associated with the total protein of many other genes, with 18 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMRAL2P-associated genes across cancer lineages are A-Raf_pS299, GAPDH, and eIF4E. Each is linked with NMRAL2P in more than 1 cancer types. Because this analysis shows association rather than direction, both NMRAL2P-to-partner and partner-to-NMRAL2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, A-Raf_pS299 grouped by NMRAL2P-low versus NMRAL2P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRAL2P→partner) and Y-score (partner→NMRAL2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	A-Raf_pS299 →	-0.241	-3.169	<.001	.020	3	1
UCEC	GAPDH →	+0.627	+3.169	.033	.020	3	1
UCEC	eIF4E →	+0.269	+3.169	.020	.020	2	1
UCEC	ACC1 →	+0.524	+3.169	.008	.019	2	1
UCEC	MEK1 →	+0.682	+3.169	<.001	.019	2	1
UCEC	p62 Lck ligand →	+0.504	+2.817	.004	.036	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

A-Raf_pS299 by NMRAL2P expression — UCEC

Explore this box plot interactively →