NMRAL2P

Across TCGA pan-cancer cohorts, NMRAL2P RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of NMRAL2P’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NMRAL2P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NMRAL2P is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where NMRAL2P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NMRAL2P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+2.558	<.001	12	view →
COAD	Female	II,III,IV	−1.335	<.001	10	view →
LIHC	Male	II,III,IV	+2.872	<.001	9	view →
LUSC	Male	All	+2.816	<.001	7	view →
LUAD	All	II,III,IV	+0.974	<.001	7	view →
UCEC	All	All	+0.665	<.001	6	view →
BRCA	All	III,IV	−0.298	.002	6	view →
KIRC	Female	III,IV	−0.564	.005	4	view →
STAD	All	IV	−0.316	.009	4	view →
KIRP	All	II,III,IV	+1.241	.016	3	view →
READ	All	II,III,IV	−0.875	.029	3	view →
CHOL	Male	All	+2.100	.029	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

NMRAL2P–HNSC

Open the HNSC breakdown →