NMNAT3

Across TCGA cell cohorts, NMNAT3 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NMNAT3-associated genes across cancer lineages are TRARG1 and UBE2QL1. Each is linked with NMNAT3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMNAT3-to-partner and partner-to-NMNAT3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRARG1 grouped by NMNAT3-low versus NMNAT3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMNAT3→partner) and Y-score (partner→NMNAT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRARG1 →	+0.027	+3.930	<.001	.003	3	1
LARGE_INTESTINE	UBE2QL1 →	+0.345	+3.722	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

TRARG1 by NMNAT3 expression — LARGE_INTESTINE

Explore this box plot interactively →