NME9

Across TCGA patient cohorts, NME9 mutation is significantly associated with the RNA expression of many other genes, with 1,117 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NME9-associated genes across cancer lineages are MIR877, RNU6-1274P, and OR6K5P. Each is linked with NME9 in more than 2 cancer types. Because this analysis shows association rather than direction, both NME9-to-partner and partner-to-NME9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR877 grouped by NME9-low versus NME9-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME9→partner) and Y-score (partner→NME9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR877 →	+0.337	+5.241	<.001	.007	3	3
READ	RNU6-1274P →	+0.547	+5.925	<.001	.002	3	2
READ	OR6K5P →	+0.057	+6.257	<.001	.001	3	2
BLCA	RNU7-56P →	+0.528	+5.147	<.001	.003	3	2
SKCM	RNU6-694P →	+0.164	+4.624	<.001	.005	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,117 associations by consensus.

MIR877 by NME9 expression — HNSC

Explore this box plot interactively →