NME9

Across TCGA cell cohorts, NME9 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NME9-associated genes across cancer lineages are DCD, OR6C2, and C7orf77. Each is linked with NME9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NME9-to-partner and partner-to-NME9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCD grouped by NME9-low versus NME9-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME9→partner) and Y-score (partner→NME9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	DCD →	+0.068	+4.977	.001	.007	3	1
SKIN	OR6C2 →	+0.022	+4.977	<.001	.007	3	1
SKIN	C7orf77 →	+0.089	+5.415	<.001	.004	3	1
LARGE_INTESTINE	SYT10 →	+0.166	+3.196	.001	.007	3	1
LARGE_INTESTINE	SPIC →	+0.207	+3.510	<.001	.003	3	1
LARGE_INTESTINE	REG1B →	+2.360	+3.196	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

DCD by NME9 expression — SKIN

Explore this box plot interactively →