NME3

Across TCGA patient cohorts, NME3 protein abundance is significantly associated with the RNA expression of many other genes, with 15,058 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NME3-associated genes across cancer lineages are VRK1, CDKN3, and CENPI. Each is linked with NME3 in more than 7 cancer types. Because this analysis shows association rather than direction, both NME3-to-partner and partner-to-NME3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME3 versus VRK1 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME3→partner) and Y-score (partner→NME3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	VRK1 →	-0.674	-0.230	<.001	<.001	3	8
LUAD	CDKN3 →	-1.147	-0.330	<.001	<.001	3	7
UCEC	CENPI →	-0.694	-0.365	.002	<.001	3	7
UCEC	UBE2S →	-0.926	-0.451	<.001	<.001	3	7
LSCC	TTK →	-1.131	-0.289	<.001	<.001	3	7
UCEC	LMNB1 →	-0.864	-0.302	<.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,058 associations by consensus.

NME3 vs VRK1 — LSCC

Explore this scatter interactively →