NME2P2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NME2P2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated NME2P2 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher NME2P2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NME2P2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and LUAD show a favorable association.

STAD, THYM, and LIHC are the cancer types where NME2P2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADDFSTertileII,III,IV0.4380.743<.00196view →
THYMOSTertileAll0.3390.893.00178view →
LIHCOSTertileII,III,IV0.3070.718<.00175view →
ESCAOSTertileIII,IV0.8830.344.00229view →
MESOOSTertileIII,IV0.4110.604.02818view →
KIRPOSTertileIII,IV0.1900.573.00718view →
LUADDFSTertileAll0.8820.774.02915view →
DLBCDFSTertileAll1.0000.381.00813view →
KIRCDFSQuartileIV0.2220.513.02112view →
HNSCDFSTertileIII,IV0.4780.286.0309view →
UCECOSQuartileIV0.8520.388.0348view →
LAMLDFSMedianAll0.5060.302.0404view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration