Across TCGA pan-cancer cohorts, NME2P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of NME2P2’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where NME2P2 RNA is repressed in tumor relative to normal tissue. In most cancer types NME2P2 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA and KIRC are the cancer types where NME2P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NME2P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.056	.013	2	view →
KIRC	Male	All	+0.026	.032	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: NME2P2 RNA expression & survival · all NME2P2 data types