NMD3

Across TCGA patient cohorts, NMD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,856 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NMD3-associated proteins across cancer lineages are RUVBL2, FXR1, and GMPS. Each is linked with NMD3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NMD3-to-partner and partner-to-NMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NMD3 versus RUVBL2 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NMD3→partner) and Y-score (partner→NMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RUVBL2 →	+0.317	+0.503	<.001	<.001	3	6
LSCC	FXR1 →	+0.470	+0.540	<.001	<.001	3	6
LSCC	GMPS →	+0.586	+0.598	<.001	<.001	3	6
LSCC	MCM3 →	+0.676	+0.701	<.001	<.001	3	6
LSCC	DBR1 →	+0.271	+0.414	<.001	<.001	3	5
LSCC	POLR1E →	+0.307	+0.455	.001	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,856 associations by consensus.

NMD3 vs RUVBL2 — LSCC

Explore this scatter interactively →