NMD3

Across TCGA patient cohorts, NMD3 mutation is significantly associated with the immune_cell of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMD3-associated genes across cancer lineages are MPP, Myocytes, and Eosinophils. Each is linked with NMD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMD3-to-partner and partner-to-NMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MPP grouped by NMD3-low versus NMD3-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMD3→partner) and Y-score (partner→NMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MPP →	+0.014	+2.519	.048	.007	3	2
SKCM	Myocytes →	+0.053	+3.201	.008	.010	2	2
LUSC	Eosinophils →	+0.040	+2.588	<.001	.036	3	1
UCEC	Erythrocytes →	+0.049	+3.241	<.001	.009	3	1
UCEC	mv Endothelial cells →	-0.033	-3.159	.012	.020	3	1
SKCM	Macrophages M2 →	-0.023	-3.099	.035	.020	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

MPP by NMD3 expression — SKCM

Explore this box plot interactively →