NMD3

Across TCGA cell cohorts, NMD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,014 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NMD3-associated GO terms across cancer lineages are Ribosomal large subunit export from nucleus, Positive regulation of protein localization to nucleolus, and Response to arsenite ion. Each is linked with NMD3 in more than 17 cancer types. Because this analysis shows association rather than direction, both NMD3-to-partner and partner-to-NMD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosomal large subunit export from nucleus grouped by NMD3-low versus NMD3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMD3→partner) and Y-score (partner→NMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Ribosomal large subunit export from nucleus →	+0.109	+1.174	<.001	<.001	3	18
BONE	Positive regulation of protein localization to nucleolus →	+0.169	+0.835	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Response to arsenite ion →	+0.141	+0.667	<.001	.001	3	13
LUNG_NSCLC_LUSC	Cellular response to arsenite ion →	+0.141	+0.667	<.001	.001	3	13
OVARY	Ribosome localization →	+0.118	+0.859	.001	<.001	3	12
OVARY	Ribosomal subunit export from nucleus →	+0.118	+0.859	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,014 associations by consensus.

Ribosomal large subunit export from nucleus by NMD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →