NMBR

Across TCGA patient cohorts, NMBR RNA expression is significantly associated with the go_rna of many other GO terms, with 7,121 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NMBR-associated GO terms across cancer lineages are Intraciliary transport, Smoothened signaling pathway, and Rescue of stalled ribosome. Each is linked with NMBR in more than 25 cancer types. Because this analysis shows association rather than direction, both NMBR-to-partner and partner-to-NMBR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by NMBR-low versus NMBR-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMBR→partner) and Y-score (partner→NMBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Intraciliary transport →	+0.045	+0.255	<.001	<.001	3	26
ESCA	Smoothened signaling pathway →	+0.053	+0.130	<.001	<.001	3	25
ESCA	Rescue of stalled ribosome →	+0.060	+0.088	<.001	.001	3	24
STAD	Regulation of autophagosome assembly →	+0.058	+0.113	<.001	<.001	3	24
STAD	Regulation of macroautophagy →	+0.060	+0.126	<.001	<.001	3	24
ESCA	Rac protein signal transduction →	+0.066	+0.102	<.001	.001	3	24

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,121 associations by consensus.

Intraciliary transport by NMBR expression — THYM

Explore this box plot interactively →