NMBR

Across TCGA patient cohorts, NMBR protein abundance is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMBR-associated genes across cancer lineages are TTI1, ZNF629, and HMOX2. Each is linked with NMBR in more than 1 cancer types. Because this analysis shows association rather than direction, both NMBR-to-partner and partner-to-NMBR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NMBR versus TTI1 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMBR→partner) and Y-score (partner→NMBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TTI1 →	+0.972	+0.500	<.001	.009	3	1
UCEC	ZNF629 →	+1.077	+0.500	.003	.009	3	1
UCEC	HMOX2 →	+1.657	+0.500	.007	.009	3	1
UCEC	VPS35L →	+0.906	+0.646	.001	.005	3	1
UCEC	DECR1 →	+0.812	+0.507	.009	.008	3	1
UCEC	EMC2 →	+0.458	+0.533	.002	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

NMBR vs TTI1 — UCEC

Explore this scatter interactively →