NMBR

Across TCGA cell cohorts, NMBR RNA expression is significantly associated with the go_rna of many other GO terms, with 1,438 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NMBR-associated GO terms across cancer lineages are Cell division, Protoporphyrinogen IX biosynthetic process, and Positive regulation of protein exit from endoplasmic reticulum. Each is linked with NMBR in more than 5 cancer types. Because this analysis shows association rather than direction, both NMBR-to-partner and partner-to-NMBR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cell division grouped by NMBR-low versus NMBR-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMBR→partner) and Y-score (partner→NMBR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Cell division →	+0.076	+0.064	.001	.008	3	6
OVARY	Protoporphyrinogen IX biosynthetic process →	+0.095	+0.088	.001	.004	3	5
LUNG_NSCLC_LUSC	Positive regulation of protein exit from endoplasmic reticulum →	+0.108	+0.070	.001	.005	3	5
CNS	Vesicle-mediated transport to the plasma membrane →	+0.028	+0.054	.005	.002	2	6
CNS	Macroautophagy →	+0.033	+0.063	.001	.007	3	4
CNS	L-leucine import across plasma membrane →	-0.114	-0.055	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,438 associations by consensus.

Cell division by NMBR expression — LUNG_NSCLC_LUSC

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