NLRP7

Across TCGA patient cohorts, NLRP7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,062 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NLRP7-associated proteins across cancer lineages are LSP1, HCLS1, and STK4. Each is linked with NLRP7 in more than 5 cancer types. Because this analysis shows association rather than direction, both NLRP7-to-partner and partner-to-NLRP7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRP7 versus LSP1 in COAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP7→partner) and Y-score (partner→NLRP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LSP1 →	+0.703	+0.429	<.001	<.001	3	6
BRCA	HCLS1 →	+0.650	+0.547	<.001	<.001	3	6
LSCC	STK4 →	+0.446	+0.917	<.001	<.001	3	5
COAD	CCDC88B →	+0.760	+0.368	.005	<.001	3	5
LSCC	CCDC88B_S597 →	+0.728	+0.723	.001	.006	3	5
BRCA	DOCK8 →	+0.614	+0.628	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,062 associations by consensus.

NLRP7 vs LSP1 — COAD

Explore this scatter interactively →