NLRP2

Across TCGA patient cohorts, NLRP2 protein abundance is significantly associated with the RNA expression of many other genes, with 7,146 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible NLRP2-associated genes across cancer lineages are GP6, NLRP7, and GALNT3. Each is linked with NLRP2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NLRP2-to-partner and partner-to-NLRP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLRP2 versus GP6 in UCEC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLRP2→partner) and Y-score (partner→NLRP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GP6 →	+0.921	+1.176	<.001	<.001	3	5
UCEC	NLRP7 →	+0.880	+1.531	<.001	<.001	3	3
BRCA	GALNT3 →	+1.522	+0.776	<.001	.004	3	2
LSCC	SYTL5 →	-1.454	-1.038	<.001	.001	3	2
UCEC	MX2 →	+0.719	+0.973	.003	.002	3	2
BRCA	CSF2RB →	+0.679	+0.610	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,146 associations by consensus.

NLRP2 vs GP6 — UCEC

Explore this scatter interactively →