NLGN4X

Across TCGA patient cohorts, NLGN4X protein abundance is significantly associated with the RNA expression of many other genes, with 762 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NLGN4X-associated genes across cancer lineages are SLC5A9, RBM5-AS1, and DSG2. Each is linked with NLGN4X in more than 1 cancer types. Because this analysis shows association rather than direction, both NLGN4X-to-partner and partner-to-NLGN4X results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLGN4X versus SLC5A9 in GBM, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NLGN4X→partner) and Y-score (partner→NLGN4X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SLC5A9 →	+0.697	+0.269	.003	.003	3	2
OV	RBM5-AS1 →	+0.493	+0.994	<.001	.001	3	2
GBM	DSG2 →	-0.846	-0.266	.002	<.001	3	2
OV	CRNKL1 →	-0.610	-0.867	.008	.006	3	1
OV	PIN4 →	-0.865	-0.922	<.001	.003	3	1
OV	GFUS →	-1.371	-0.875	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 762 associations by consensus.

NLGN4X vs SLC5A9 — GBM

Explore this scatter interactively →