NLGN4X

Across TCGA cell cohorts, NLGN4X RNA expression is significantly associated with the go_rna of many other GO terms, with 2,962 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NLGN4X-associated GO terms across cancer lineages are Brainstem development, Regulation of stem cell population maintenance, and Regulation of nucleobase-containing compound transport. Each is linked with NLGN4X in more than 8 cancer types. Because this analysis shows association rather than direction, both NLGN4X-to-partner and partner-to-NLGN4X results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Brainstem development grouped by NLGN4X-low versus NLGN4X-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NLGN4X→partner) and Y-score (partner→NLGN4X) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Brainstem development →	-0.243	-2.138	<.001	<.001	3	9
BONE	Regulation of stem cell population maintenance →	+0.053	+1.980	.005	.004	3	7
BONE	Regulation of nucleobase-containing compound transport →	+0.157	+2.769	<.001	<.001	3	7
BONE	Lipoprotein transport →	+0.194	+3.105	<.001	<.001	3	6
BONE	Negative regulation of transcription by RNA polymerase I →	+0.129	+2.573	<.001	<.001	3	6
LUNG_SCLC	Positive regulation of mRNA metabolic process →	+0.036	+1.481	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,962 associations by consensus.

Brainstem development by NLGN4X expression — LUNG_SCLC

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