NLGN1

Across TCGA patient cohorts, NLGN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,964 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NLGN1-associated proteins across cancer lineages are CRMP1, DCLK1, and HDGFL3. Each is linked with NLGN1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NLGN1-to-partner and partner-to-NLGN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NLGN1 versus CRMP1 in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NLGN1→partner) and Y-score (partner→NLGN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CRMP1 →	+0.679	+0.902	.001	<.001	3	5
COAD	DCLK1 →	+0.608	+0.258	<.001	<.001	3	5
UCEC	HDGFL3 →	+0.699	+0.813	<.001	<.001	3	5
LSCC	TUBB2B →	+1.190	+0.614	.005	.003	3	4
GBM	UPP1_S61 →	-0.881	-0.688	<.001	.001	3	4
GBM	CDC42EP4 →	+0.383	+0.588	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,964 associations by consensus.

NLGN1 vs CRMP1 — LSCC

Explore this scatter interactively →