NKX6-2

Across TCGA patient cohorts, NKX6-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,400 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NKX6-2-associated proteins across cancer lineages are ELAPOR2, LMAN1, and ACSS1. Each is linked with NKX6-2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NKX6-2-to-partner and partner-to-NKX6-2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKX6-2 versus ELAPOR2 in CCRCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX6-2→partner) and Y-score (partner→NKX6-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ELAPOR2 →	+0.726	+0.106	.002	.008	3	3
CCRCC	LMAN1 →	-0.349	-0.114	<.001	.001	3	3
PDAC	ACSS1 →	+0.422	+0.618	.003	.002	3	3
CCRCC	GUCY1B1 →	+0.302	+0.104	.002	.003	3	3
GBM	SEPTIN4_S117 →	+1.289	+2.235	<.001	<.001	3	3
GBM	IQSEC1_S180 →	+0.364	+1.344	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,400 associations by consensus.

NKX6-2 vs ELAPOR2 — CCRCC

Explore this scatter interactively →