NKX3-2

Across TCGA patient cohorts, NKX3-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,273 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NKX3-2-associated proteins across cancer lineages are ISLR, RCN3, and SULF1. Each is linked with NKX3-2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NKX3-2-to-partner and partner-to-NKX3-2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKX3-2 versus ISLR in OV, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX3-2→partner) and Y-score (partner→NKX3-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ISLR →	+0.980	+1.251	<.001	<.001	3	8
OV	RCN3 →	+0.763	+1.256	<.001	<.001	3	8
OV	SULF1 →	+1.090	+1.353	<.001	<.001	3	8
OV	THBS2 →	+1.895	+1.373	<.001	<.001	3	8
OV	COMP →	+1.434	+1.262	<.001	<.001	3	8
OV	TIMP2 →	+0.800	+1.286	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,273 associations by consensus.

NKX3-2 vs ISLR — OV

Explore this scatter interactively →