NKX3-2

Across TCGA patient cohorts, NKX3-2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,978 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NKX3-2-associated genes across cancer lineages are SRRM1, RNU6-238P, and PHACTR4. Each is linked with NKX3-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKX3-2-to-partner and partner-to-NKX3-2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKX3-2 versus SRRM1 in LSCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX3-2→partner) and Y-score (partner→NKX3-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRRM1 →	+0.743	+0.811	.008	.007	3	2
UCEC	RNU6-238P →	+1.174	+0.356	.005	.009	3	2
LSCC	PHACTR4 →	+0.635	+0.665	.003	.003	3	2
UCEC	SNORA10B →	+1.148	+0.404	.004	<.001	3	2
UCEC	FAM13A-AS1 →	+0.633	+0.476	.002	.001	3	2
UCEC	MIR302CHG →	+0.906	+0.523	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,978 associations by consensus.

NKX3-2 vs SRRM1 — LSCC

Explore this scatter interactively →