NKX3-2

Across TCGA cell cohorts, NKX3-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,152 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NKX3-2-associated GO terms across cancer lineages are Electron transport chain, Oxidative phosphorylation, and Ribonucleoside triphosphate biosynthetic process. Each is linked with NKX3-2 in more than 8 cancer types. Because this analysis shows association rather than direction, both NKX3-2-to-partner and partner-to-NKX3-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Electron transport chain grouped by NKX3-2-low versus NKX3-2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NKX3-2→partner) and Y-score (partner→NKX3-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Electron transport chain →	+0.120	+0.313	<.001	.002	3	9
OESOPHAGUS	Oxidative phosphorylation →	+0.128	+0.290	.002	<.001	3	9
OESOPHAGUS	Ribonucleoside triphosphate biosynthetic process →	+0.139	+0.323	<.001	.001	3	9
SKIN	Proton motive force-driven ATP synthesis →	+0.090	+0.569	<.001	<.001	3	9
OESOPHAGUS	Regulation of blood circulation →	-0.095	-0.277	<.001	<.001	3	9
OESOPHAGUS	Regulation of postsynaptic membrane potential →	-0.112	-0.186	.003	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,152 associations by consensus.

Electron transport chain by NKX3-2 expression — OESOPHAGUS

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