Q-omics provides the consensus-scored NKAPP1 profile across patient tissues and cancer cell-line models. NKAPP1 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, NKAPP1 is differentially expressed in 14, with the highest sampling consensus in KIRC. Additionally, NKAPP1 RNA expression shows 20,372 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight MESO, KIRC, and KIRP as cancer lineages where NKAPP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NKAPP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NKAPP1 survival associations across molecular data types. NKAPP1 RNA expression shows survival associations in the most cancer types (21), followed by mutation status (1). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NKAPP1 RNA expression–survival associations across cancer types. High NKAPP1 expression shows unfavorable associations in HNSC, but favorable associations in MESO, BRCA, CESC, SKCM and KIRC. The MESO Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify MESO as the clearest survival context for NKAPP1 RNA expression.
This table summarizes NKAPP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for NKAPP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NKAPP1 shows lower tumor expression in UCEC and BRCA and higher tumor expression in KIRC, LIHC, COAD and HNSC. The KIRC box plot shows higher NKAPP1 RNA expression in tumor versus normal tissue (log2 FC = +0.353, t-test p < 0.001).
This table shows molecular features associated with NKAPP1 in patient tissues and cancer cell lines. In patient samples, NKAPP1 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
