Across TCGA patient cohorts, NKAPL mutation is significantly associated with the RNA expression of many other genes, with 5,675 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAPL-associated genes across cancer lineages are OXNAD1, MED8, and GMEB1. Each is linked with NKAPL in more than 2 cancer types. Because this analysis shows association rather than direction, both NKAPL-to-partner and partner-to-NKAPL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAPL→partner) and Y-score (partner→NKAPL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OXNAD1 →	+0.242	+1.968	.008	<.001	3	3
UCEC	MED8 →	+0.291	+3.346	.001	<.001	3	3
COAD	GMEB1 →	+0.397	+2.235	<.001	.006	3	3
UCEC	DCAF16 →	+0.439	+3.906	.001	<.001	3	3
UCEC	NME6 →	+0.293	+1.538	<.001	.003	3	3
UCEC	UQCRH →	+0.641	+3.032	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,675 associations by consensus.

Exploration

NKAPL survival (RNA) · tumor vs normal (RNA) · all NKAPL data types