NKAP

Across TCGA patient cohorts, NKAP protein abundance is significantly associated with the RNA expression of many other genes, with 9,609 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NKAP-associated genes across cancer lineages are ALG13, CDK2, and UPF3B. Each is linked with NKAP in more than 4 cancer types. Because this analysis shows association rather than direction, both NKAP-to-partner and partner-to-NKAP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NKAP versus ALG13 in HNSC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAP→partner) and Y-score (partner→NKAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ALG13 →	+0.551	+0.383	<.001	<.001	3	4
GBM	CDK2 →	+0.656	+0.293	<.001	.002	3	4
HNSC	UPF3B →	+0.606	+0.364	<.001	<.001	3	4
HNSC	CUL4B →	+0.401	+0.220	<.001	<.001	3	4
LSCC	ZBTB33 →	+0.723	+0.324	<.001	<.001	3	4
HNSC	CXorf56 →	+0.533	+0.331	.002	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,609 associations by consensus.

NKAP vs ALG13 — HNSC

Explore this scatter interactively →