NKAP

Across TCGA patient cohorts, NKAP mutation is significantly associated with the RNA expression of many other genes, with 5,149 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAP-associated genes across cancer lineages are RNU2-71P, CCT3P1, and MIR6766. Each is linked with NKAP in more than 2 cancer types. Because this analysis shows association rather than direction, both NKAP-to-partner and partner-to-NKAP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU2-71P grouped by NKAP-low versus NKAP-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAP→partner) and Y-score (partner→NKAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU2-71P →	+0.283	+6.444	<.001	.001	3	3
BLCA	CCT3P1 →	+0.036	+4.289	.001	.007	3	2
LUAD	MIR6766 →	+0.546	+6.087	<.001	.002	3	2
LUSC	SNORD114-4 →	+0.392	+4.882	.002	.005	3	2
LUSC	EIF3JP1 →	+0.242	+4.236	<.001	.008	3	2
BRCA	IFNA16 →	+0.039	+5.324	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,149 associations by consensus.

RNU2-71P by NKAP expression — LUAD

Explore this box plot interactively →