NKAIN4

Across TCGA patient cohorts, NKAIN4 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAIN4-associated genes across cancer lineages are MIR3619, BCRP6, and PRM3. Each is linked with NKAIN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAIN4-to-partner and partner-to-NKAIN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3619 grouped by NKAIN4-low versus NKAIN4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN4→partner) and Y-score (partner→NKAIN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR3619 →	+0.945	+4.188	<.001	.009	3	1
UCEC	BCRP6 →	+0.156	+4.661	<.001	.004	3	1
UCEC	PRM3 →	+0.236	+4.748	<.001	.003	3	1
COAD	RNU6-1138P →	+0.338	+4.790	.002	.006	3	1
COAD	RNU6-784P →	+0.340	+4.516	<.001	.009	3	1
COAD	TRAJ46 →	+0.579	+4.516	.005	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

MIR3619 by NKAIN4 expression — UCEC

Explore this box plot interactively →