Across TCGA cell cohorts, NKAIN3 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NKAIN3-associated genes across cancer lineages are PSKH2, MBD3L4, and GALNTL5. Each is linked with NKAIN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NKAIN3-to-partner and partner-to-NKAIN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN3→partner) and Y-score (partner→NKAIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PSKH2 →	+0.021	+4.887	<.001	.009	3	2
LUNG_NSCLC_LUAD	MBD3L4 →	+0.023	+6.266	<.001	<.001	3	1
SKIN	GALNTL5 →	+0.029	+4.415	<.001	.007	3	1
SKIN	IL22 →	+0.015	+5.022	<.001	.002	3	1
SKIN	HES3 →	+0.062	+5.022	<.001	.002	3	1
SKIN	ENPP7 →	+0.009	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

NKAIN3 survival (RNA) · tumor vs normal (RNA) · all NKAIN3 data types