Across TCGA patient cohorts, NKAIN2 mutation is significantly associated with the RNA expression of many other genes, with 2,118 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NKAIN2-associated genes across cancer lineages are LINC01399, H3P34, and SNRPGP6. Each is linked with NKAIN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NKAIN2-to-partner and partner-to-NKAIN2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NKAIN2→partner) and Y-score (partner→NKAIN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC01399 →	+0.244	+1.892	<.001	.008	3	3
BRCA	H3P34 →	+0.083	+5.841	<.001	.003	3	2
CESC	SNRPGP6 →	+0.068	+4.030	<.001	.008	3	2
UCEC	GPR180 →	+0.519	+3.346	.004	.005	3	2
UCEC	SUPV3L1 →	+0.493	+2.601	.001	.006	3	2
UCEC	ZC3H18 →	+0.552	+3.724	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,118 associations by consensus.

Exploration

NKAIN2 survival (RNA) · tumor vs normal (RNA) · all NKAIN2 data types