NIT2

Across TCGA patient cohorts, NIT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,930 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NIT2-associated proteins across cancer lineages are ZNF638, RUVBL2, and DBR1. Each is linked with NIT2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NIT2-to-partner and partner-to-NIT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NIT2 versus ZNF638 in HNSC, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NIT2→partner) and Y-score (partner→NIT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF638 →	+0.252	+0.585	<.001	<.001	3	6
LSCC	RUVBL2 →	+0.261	+0.395	<.001	<.001	3	6
LSCC	DBR1 →	+0.348	+0.411	<.001	<.001	3	6
PDAC	RUVBL1 →	+0.311	+0.255	<.001	<.001	3	6
LUAD	NUP214 →	+0.155	+0.379	<.001	.002	3	5
OV	PCNP →	+0.293	+0.341	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,930 associations by consensus.

NIT2 vs ZNF638 — HNSC

Explore this scatter interactively →