NIT1

Across TCGA patient cohorts, NIT1 mutation is significantly associated with the RNA expression of many other genes, with 585 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NIT1-associated genes across cancer lineages are MIR1200, RPL32P19, and MIR1197. Each is linked with NIT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NIT1-to-partner and partner-to-NIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR1200 grouped by NIT1-low versus NIT1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIT1→partner) and Y-score (partner→NIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR1200 →	+1.728	+5.044	<.001	.009	3	2
COAD	RPL32P19 →	+0.177	+4.602	<.001	.001	3	2
STAD	MIR1197 →	+0.269	+4.678	<.001	.007	3	2
COAD	VWC2L-IT1 →	+0.130	+5.136	.004	.002	3	2
LUSC	PHBP15 →	+0.081	+5.548	<.001	.004	3	2
LUAD	OR51A9P →	+0.139	+4.990	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 585 associations by consensus.

MIR1200 by NIT1 expression — LUAD

Explore this box plot interactively →