NIPSNAP3B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NIPSNAP3B mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NIPSNAP3B-associated genes across cancer lineages are C10orf53 and FGF23. Each is linked with NIPSNAP3B in more than 1 cancer types. Because this analysis shows association rather than direction, both NIPSNAP3B-to-partner and partner-to-NIPSNAP3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C10orf53 grouped by NIPSNAP3B-low versus NIPSNAP3B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPSNAP3B→partner) and Y-score (partner→NIPSNAP3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEC10orf53 →+0.015+4.047<.001<.00131
LARGE_INTESTINEFGF23 →+0.431+3.584.002.00321
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

C10orf53 by NIPSNAP3B expression — LARGE_INTESTINE

Box plot of C10orf53 in NIPSNAP3B-low vs NIPSNAP3B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration