Across TCGA patient cohorts, NIPSNAP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,516 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NIPSNAP1-associated proteins across cancer lineages are SMC4, MCM2_S139, and MCM3. Each is linked with NIPSNAP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NIPSNAP1-to-partner and partner-to-NIPSNAP1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPSNAP1→partner) and Y-score (partner→NIPSNAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SMC4 →	+0.498	+0.578	<.001	<.001	3	7
LSCC	MCM2_S139 →	+0.588	+0.503	<.001	<.001	3	7
LSCC	MCM3 →	+0.697	+0.623	<.001	<.001	3	7
LSCC	MCM5 →	+0.661	+0.639	<.001	<.001	3	7
UCEC	NCAPH →	+0.733	+0.833	<.001	<.001	3	7
LSCC	RFC1_S368 →	+0.636	+0.554	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,516 associations by consensus.

Exploration

NIPSNAP1 survival (RNA) · tumor vs normal (RNA) · all NIPSNAP1 data types