NIPAL4

Across TCGA patient cohorts, NIPAL4 mutation is significantly associated with the RNA expression of many other genes, with 586 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NIPAL4-associated genes across cancer lineages are RN7SL248P, CYCSP12, and RRM1. Each is linked with NIPAL4 in more than 2 cancer types. Because this analysis shows association rather than direction, both NIPAL4-to-partner and partner-to-NIPAL4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by NIPAL4-low versus NIPAL4-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIPAL4→partner) and Y-score (partner→NIPAL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RN7SL248P →	+0.066	+4.000	<.001	.009	3	3
COAD	CYCSP12 →	+0.352	+5.283	<.001	.006	3	3
SKCM	RRM1 →	+0.565	+2.839	.009	.001	3	3
LUAD	RNU4-41P →	+0.184	+4.155	.001	.007	3	2
LUAD	RNA5SP379 →	+0.674	+3.927	<.001	.002	3	2
LUAD	ATP5MFP1 →	+0.193	+2.896	.006	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 586 associations by consensus.

RN7SL248P by NIPAL4 expression — LUAD

Explore this box plot interactively →