NIPA2P4

Across TCGA pan-cancer cohorts, NIPA2P4 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated NIPA2P4 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher NIPA2P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NIPA2P4 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LIHC show a favorable association.

READ, THYM, and SARC are the cancer types where NIPA2P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	III,IV	0.111	0.890	<.001	54	view →
THYM	DFS	Tertile	II,III,IV	0.166	0.770	<.001	42	view →
SARC	OS	Tertile	All	0.402	0.759	<.001	36	view →
ESCA	DFS	Median	All	0.290	0.482	.003	33	view →
COAD	OS	Tertile	IV	0.251	0.681	.006	27	view →
MESO	DFS	Tertile	III,IV	0.078	0.376	.012	27	view →
KIRP	OS	Tertile	All	0.249	0.717	.005	27	view →
LUAD	DFS	Tertile	All	0.636	0.329	.019	21	view →
PAAD	OS	Tertile	All	0.228	0.645	.013	18	view →
LIHC	OS	Tertile	III,IV	1.000	0.313	.032	9	view →
LAML	DFS	Median	All	0.291	0.430	.046	4	view →
STAD	DFS	Median	III,IV	0.257	0.573	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

NIPA2P4–READ (OS)

Open the READ breakdown →