NIPA2P4

Across TCGA pan-cancer cohorts, NIPA2P4 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of NIPA2P4’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NIPA2P4 RNA is repressed in tumor relative to normal tissue. In most cancer types NIPA2P4 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, HNSC, and THCA are the cancer types where NIPA2P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NIPA2P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	All	III,IV	−0.030	.021	4	view →
HNSC	All	IV	+0.019	.022	2	view →
THCA	All	All	−0.007	.017	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

NIPA2P4–LUAD

Open the LUAD breakdown →