NINL

Across TCGA patient cohorts, NINL protein abundance is significantly associated with the RNA expression of many other genes, with 17,590 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NINL-associated genes across cancer lineages are LARP4, DNAJC5, and POLI. Each is linked with NINL in more than 1 cancer types. Because this analysis shows association rather than direction, both NINL-to-partner and partner-to-NINL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NINL versus LARP4 in LSCC, with a Pearson correlation of -0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NINL→partner) and Y-score (partner→NINL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	LARP4 →	-0.574	-0.759	.006	<.001	3	2
CCRCC	DNAJC5 →	-0.499	-0.651	.001	.001	3	1
CCRCC	POLI →	+0.620	+0.553	.009	.006	3	1
CCRCC	BEX4 →	+0.913	+0.671	.007	<.001	3	1
CCRCC	DTWD1 →	+0.455	+0.769	.008	.009	3	1
CCRCC	PKD2L1 →	-0.600	-0.493	.006	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,590 associations by consensus.

NINL vs LARP4 — LSCC

Explore this scatter interactively →