NINL

Across TCGA cell cohorts, NINL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,975 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NINL-associated GO terms across cancer lineages are Regulation of RNA splicing, Regulation of mRNA processing, and Regulation of DNA-templated transcription initiation. Each is linked with NINL in more than 15 cancer types. Because this analysis shows association rather than direction, both NINL-to-partner and partner-to-NINL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by NINL-low versus NINL-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NINL→partner) and Y-score (partner→NINL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of RNA splicing →	+0.109	+2.335	<.001	<.001	3	16
OESOPHAGUS	Regulation of mRNA processing →	+0.089	+1.862	<.001	<.001	3	16
OESOPHAGUS	Regulation of DNA-templated transcription initiation →	+0.114	+2.020	<.001	<.001	3	16
OESOPHAGUS	Cytoplasmic translation →	+0.166	+2.304	<.001	<.001	3	15
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.213	+2.075	<.001	<.001	3	15
OESOPHAGUS	Regulation of DNA-templated transcription elongation →	+0.080	+1.761	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,975 associations by consensus.

Regulation of RNA splicing by NINL expression — OESOPHAGUS

Explore this box plot interactively →