NINJ1

Across TCGA cell cohorts, NINJ1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,548 significant associations in total. CNS shows the largest number of these associations.

The most reproducible NINJ1-associated GO terms across cancer lineages are Pyroptotic cell death, Leukocyte chemotaxis involved in inflammatory response, and Lysosomal lumen acidification. Each is linked with NINJ1 in more than 14 cancer types. Because this analysis shows association rather than direction, both NINJ1-to-partner and partner-to-NINJ1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyroptotic cell death grouped by NINJ1-low versus NINJ1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NINJ1→partner) and Y-score (partner→NINJ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Pyroptotic cell death →	+1.032	+1.270	<.001	<.001	3	15
CNS	Leukocyte chemotaxis involved in inflammatory response →	+0.693	+1.975	<.001	<.001	3	15
SOFT_TISSUE	Lysosomal lumen acidification →	+0.080	+0.989	<.001	<.001	3	11
BONE	Regulation of monocyte chemotaxis →	+0.229	+1.105	<.001	<.001	3	11
BONE	Cytolysis →	+1.138	+1.608	.001	<.001	3	11
BONE	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.198	+1.382	.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,548 associations by consensus.

Pyroptotic cell death by NINJ1 expression — LUNG_SCLC

Explore this box plot interactively →