NIN

Across TCGA cell cohorts, NIN RNA expression is significantly associated with the go_rna of many other GO terms, with 5,504 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NIN-associated GO terms across cancer lineages are Microtubule polymerization, Microtubule polymerization or depolymerization, and Microtubule nucleation by microtubule organizing center. Each is linked with NIN in more than 17 cancer types. Because this analysis shows association rather than direction, both NIN-to-partner and partner-to-NIN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule polymerization grouped by NIN-low versus NIN-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIN→partner) and Y-score (partner→NIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Microtubule polymerization →	+0.126	+1.862	<.001	<.001	3	18
STOMACH	Microtubule polymerization or depolymerization →	+0.131	+1.841	<.001	<.001	3	17
STOMACH	Microtubule nucleation by microtubule organizing center →	+0.217	+1.918	<.001	<.001	3	17
KIDNEY	Microtubule nucleation →	+0.132	+1.521	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.078	+0.870	.001	.001	3	16
KIDNEY	Centrosome localization →	+0.116	+1.355	.001	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,504 associations by consensus.

Microtubule polymerization by NIN expression — STOMACH

Explore this box plot interactively →