NIFKP8

Across TCGA patient cohorts, NIFKP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,135 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NIFKP8-associated GO terms across cancer lineages are Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, Transcription by RNA polymerase III, and Nuclear export. Each is linked with NIFKP8 in more than 18 cancer types. Because this analysis shows association rather than direction, both NIFKP8-to-partner and partner-to-NIFKP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay grouped by NIFKP8-low versus NIFKP8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIFKP8→partner) and Y-score (partner→NIFKP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.038	+0.044	<.001	<.001	3	19
STAD	Transcription by RNA polymerase III →	+0.036	+0.042	<.001	<.001	3	19
STAD	Nuclear export →	+0.042	+0.039	<.001	<.001	3	18
STAD	Protein K48-linked deubiquitination →	+0.035	+0.042	<.001	<.001	3	18
STAD	Protein-containing complex localization →	+0.030	+0.035	<.001	<.001	3	18
STAD	Recombinational repair →	+0.037	+0.045	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,135 associations by consensus.

Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay by NIFKP8 expression — STAD

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