NIFKP6

Across TCGA pan-cancer cohorts, NIFKP6 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated NIFKP6 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher NIFKP6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NIFKP6 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCS show a favorable association.

KIRP, KIRC, and ACC are the cancer types where NIFKP6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Tertile	All	0.847	0.951	.002	84	view →
KIRC	OS	Median	All	0.568	0.690	.002	73	view →
ACC	OS	Tertile	All	0.280	0.740	<.001	67	view →
LIHC	OS	Tertile	II,III,IV	0.285	0.673	<.001	63	view →
COAD	OS	Median	II,III,IV	0.910	0.805	.003	32	view →
UCS	OS	Median	III,IV	0.718	0.429	.028	28	view →
MESO	DFS	Tertile	All	0.124	0.483	.016	27	view →
OV	OS	Quartile	III,IV	0.307	0.443	.009	26	view →
BLCA	OS	Median	III,IV	0.625	0.489	.009	19	view →
PRAD	OS	Tertile	All	0.976	0.998	<.001	18	view →
UCEC	DFS	Median	All	0.786	0.866	.004	16	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

NIFKP6–KIRP (OS)

Open the KIRP breakdown →