NIFKP4

Across TCGA patient cohorts, NIFKP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,466 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NIFKP4-associated GO terms across cancer lineages are Regulation of mitochondrial gene expression, Nucleobase-containing compound transport, and Positive regulation of proteasomal protein catabolic process. Each is linked with NIFKP4 in more than 12 cancer types. Because this analysis shows association rather than direction, both NIFKP4-to-partner and partner-to-NIFKP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial gene expression grouped by NIFKP4-low versus NIFKP4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NIFKP4→partner) and Y-score (partner→NIFKP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of mitochondrial gene expression →	+0.061	+0.190	<.001	<.001	3	13
ESCA	Nucleobase-containing compound transport →	+0.075	+0.190	<.001	<.001	3	13
ESCA	Positive regulation of proteasomal protein catabolic process →	+0.078	+0.188	<.001	<.001	3	13
ESCA	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.059	+0.130	<.001	<.001	3	13
ESCA	mRNA 3'-end processing →	+0.073	+0.164	<.001	<.001	3	13
ESCA	DNA integrity checkpoint signaling →	+0.075	+0.193	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,466 associations by consensus.

Regulation of mitochondrial gene expression by NIFKP4 expression — STAD

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