NIFK-AS1

Across TCGA pan-cancer cohorts, NIFK-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated NIFK-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher NIFK-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated NIFK-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and LUAD show a favorable association.

BRCA, ACC, and LIHC are the cancer types where NIFK-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	All	0.623	0.537	<.001	88	view →
ACC	DFS	Median	All	0.192	0.687	<.001	87	view →
LIHC	DFS	Median	All	0.465	0.614	<.001	65	view →
LUAD	DFS	Quartile	All	0.798	0.495	<.001	50	view →
MESO	OS	Median	All	0.731	0.292	.002	40	view →
OV	OS	Tertile	IV	0.855	0.635	.001	40	view →
COAD	DFS	Quartile	All	0.375	0.634	.004	31	view →
KIRC	OS	Median	All	0.691	0.571	.007	15	view →
KICH	DFS	Tertile	II,III,IV	0.560	1.000	.018	14	view →
ESCA	OS	Tertile	II,III,IV	0.835	0.623	.013	8	view →
KIRP	DFS	Tertile	All	1.000	0.839	.035	8	view →
PAAD	DFS	Median	All	0.587	0.417	.028	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

NIFK-AS1–BRCA (OS)

Open the BRCA breakdown →