NIFK-AS1

Across TCGA pan-cancer cohorts, NIFK-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NIFK-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where NIFK-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types NIFK-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, LIHC, and THCA are the cancer types where NIFK-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NIFK-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	All	−1.794	<.001	11	view →
LIHC	Female	II,III,IV	+0.882	<.001	9	view →
THCA	Male	All	−0.598	<.001	9	view →
LUAD	Female	III,IV	−0.842	<.001	7	view →
UCEC	All	All	−1.066	<.001	6	view →
BRCA	All	II,III,IV	−0.615	<.001	6	view →
CHOL	All	All	+1.624	<.001	5	view →
HNSC	All	III,IV	+0.432	.006	4	view →
BLCA	Male	IV	−1.512	.001	2	view →
LUSC	All	III,IV	−0.606	.004	2	view →
PRAD	All	All	−0.321	<.001	2	view →
COAD	All	All	−0.262	.017	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NIFK-AS1–KICH

Open the KICH breakdown →