NICN2P

Across TCGA pan-cancer cohorts, NICN2P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated NICN2P data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher NICN2P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NICN2P expression acts as an unfavorable survival marker, although some lineages such as THCA and READ show a favorable association.

LIHC, THCA, and LUSC are the cancer types where NICN2P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Tertile	All	0.301	0.716	<.001	45	view →
THCA	DFS	Tertile	All	1.000	0.804	.002	33	view →
LUSC	DFS	Tertile	All	0.214	0.405	.013	27	view →
READ	DFS	Tertile	III,IV	0.764	0.329	.034	27	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
DLBC	OS	Tertile	IV	0.342	0.930	.045	18	view →
KIRP	OS	Tertile	All	1.000	0.697	.043	12	view →
STAD	DFS	Tertile	IV	0.166	0.490	.039	9	view →
PCPG	DFS	Tertile	All	0.728	0.944	.001	9	view →
ACC	DFS	Tertile	All	0.204	0.658	.008	9	view →
UCEC	DFS	Tertile	IV	0.887	0.568	.033	8	view →
COAD	OS	Tertile	II,III,IV	1.000	0.830	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

NICN2P–LIHC (OS)

Open the LIHC breakdown →