NIBAN1

Across TCGA patient cohorts, NIBAN1 mutation is significantly associated with the RNA expression of many other genes, with 5,335 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NIBAN1-associated genes across cancer lineages are SKA1, C18orf54, and SCNN1B. Each is linked with NIBAN1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NIBAN1-to-partner and partner-to-NIBAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKA1 grouped by NIBAN1-low versus NIBAN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NIBAN1→partner) and Y-score (partner→NIBAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SKA1 →	+0.903	+2.332	<.001	<.001	3	4
UCEC	C18orf54 →	+0.520	+1.678	<.001	<.001	3	4
UCEC	SCNN1B →	-1.020	-1.321	.003	.005	3	4
UCEC	PRPF4 →	+0.588	+2.908	<.001	<.001	3	4
UCEC	RCC1 →	+0.602	+1.688	<.001	<.001	3	3
UCEC	TIGD2 →	+0.464	+1.720	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,335 associations by consensus.

SKA1 by NIBAN1 expression — UCEC

Explore this box plot interactively →