Across TCGA patient cohorts, NHS protein abundance is significantly associated with the RNA expression of many other genes, with 7,079 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NHS-associated genes across cancer lineages are CHP1P3, NHS-AS1, and MIR4768. Each is linked with NHS in more than 5 cancer types. Because this analysis shows association rather than direction, both NHS-to-partner and partner-to-NHS results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NHS→partner) and Y-score (partner→NHS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CHP1P3 →	+0.958	+0.527	.001	<.001	3	6
UCEC	NHS-AS1 →	+1.069	+0.505	<.001	<.001	3	5
CCRCC	MIR4768 →	+1.012	+0.372	<.001	<.001	3	4
UCEC	SCML1 →	+0.992	+0.255	.005	.002	3	4
LUAD	REPS2 →	+0.816	+0.471	<.001	<.001	3	3
GBM	STYXL2 →	+0.550	+0.426	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,079 associations by consensus.

Exploration

NHS survival (RNA) · tumor vs normal (RNA) · all NHS data types